I have been using an extra large exo terra enclosure (36'' x 36'' x 18'' glass with vents) to successfully keep my male panther for his entire life. I use a mistking system and dripper for watering, the enclosure is bioactive and fully plumbed, and I feed a variety of feeders including wild caught insects. I recently ran a fecal sample to see if a lifetime of eating WC feeders had given him any parasites - the test was negative, it appears it had not.
I gutload my feeders with dark leafy greens, carrots, and repashy superload as my commercial gutload. I will raise roach feeders on produce and rabbit food to keep the protein down (cockroaches store excess protein as uric acid in their tissues, which can predispose chameleons to gout and kidney damage). I generally will dust feeders with calcium powder every meal, calcium with d3 once a month, and vitamins with preformed vitamin A 1-2x per month. I feed my chameleon discoid roaches, red runner roaches, banana roaches, crickets, hornworms, stick insects, superworms, silkworms (when available), BSF (when available), grasshoppers (when available), wild caught katydids (seasonal), various light trapped wild caught prey items (seasonal).
I use regular incandescent flood lights for heat and t5 tubes for UVB. I will also take my chameleon outside during appropriate weather, where I have a standard zoomed screen cage (2' x 2' x 4') set up for him so he can get natural sunlight.