Follow along with the video below to see how to install our site as a web app on your home screen.
Note: This feature may not be available in some browsers.
Toxic principle. Andromedotoxins (grayanotoxins) are water-soluble diterpenoid compounds. Leaves and flower nectar (including honey made from plant nectar) are sources of the toxin. Honey made from the plants has been reported to cause cardiac arrhythmias, emesis, mild paralysis and convulsions in humans and is known as “mad honey”.
Toxicity. As little as 3 ml nectar/kg body weight or 0.2% of the body weight as leaves may be toxic or lethal.
Mechanism of toxicologic damage. Andromedotoxins bind to and modify the sodium channels of cell membranes, leading to prolonged depolarization and excitation. Modification of the sodium channels favors calcium movement into cells and results in a positive inotropic effect similar to that of digitalis.
in other word very dangerous