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Try using a soft bristle toothbrush my Chams absolutly love it it helps with slow shedding too.I would say spray it with warm water. He might not like it. Just mist it from a distance so it is not a jet of water hitting his eye. Also, I am not 100% that that is shed. When my chameleons shed their eyes it is usually very white and flaky and usually can be removed easily. I mean it could be, but if it still remains after all your attempts then I would start considering it is something that is attached to the eye like a growth like I said before. Has he been trying to rub it off on any branches or anything himself? It looks kinda yellowy looking and bumpy not so much like left over shed. Maybe it is just the picture, I don't know.
Try using a soft bristle toothbrush my Chams absolutly love it it helps with slow shedding too.