Does my Jackson's Chameleon have MBD?

[Coheed]

The fact that her cage was too low certainly may be the cause of her stress coloration.
As for cleanliness of the cage, it probably won't stress her psychologically but it can make it much easier for her to become ill.
In the wild, a cham can get away from their poops, shed skin, etc. but in captivity, there's no escaping it.
High levels of bacteria in an area can easily lead to an infection.

As for her gaping, if it was for more than just a brief moment--could be anything ranging from she is too hot, trying to scare you away or a respiratory infection.
In the absence of other symptoms of illness, it is often nothing to be concerned about.
You can read all about cham health here.

I honestly don't know what is causing the problem with the leg.
It could be gout or a calcium buildup within the joint or a deformity of the joint caused by a defect from an injury or a malformation at birth or a nerve problem or a muscle problem.
If she was my cham, I would probably see if she improves after a week or two of changes to her diet (variety of feeders and a good insect gutload), added hydration and of her being in the better location
If the vet truly knows chameleons well, then he might be able to make a definitive diagnosis and hopefully without needing to do too many tests.
In any case, I'm not sure that there would be anything that could be done to resolve the leg issue or any organ damage, if any has occurred.
I would certainly be sure to mention that she was inadvertently given much more D3 than she should have been, if I went to the vet with her.
It could help the vet to make an accurate diagnosis much more easily.
If the vet does not have a good deal of experience with chams, then you may want to pass on the vet visit.
Vets who just have a general idea about cham care can, and sometimes do, make a cham much worse.

Thank you guys so much for the input! I will be making the correct adjustments to her diet and moisture starting tomorrow(this is when she is scheduled to eat next) and I sincerely hope to see some improvement after a few weeks of the change, I have a lot of hope. She doesn't seem all that sick and her condition isn't worsening as days pass she just seems uncomfortable. As for her leg she does handle it well and it doesn't happen often at all, maybe once a month. Ill hold off on the vet visit for a few weeks because I too am weary of exotic vets, how could they possibly have a full understanding of all species of captive Chams? Im worried they will impose a generalized treatment that will make her even worse. Thanks again everyone who contributed to this thread for putting up with my ignorance and for providing me with such helpful info!