Ok. Yea they still need the hydration, just do not spray them directly. Chameleons are dry shedders and getting them wet will make the shed stick. So still mist the cage, he will still need to drink.
Hopefully it’s just dehydration or stress. I’m not an expert and I’m just going off of what I have learned here on the forum. I would watch him very closely and make note of any other symptoms or signs. Typically it is not a good sign when eyes sink in, but I don’t want you to panic or freak out. I just want you to monitor and tell us of any other changes at all. Since it can be so many things, it’s just not enough to go off of. Chameleons are soooo good at hiding illness. Since they do not have many defenses, they will pretend they are ok until they just can’t. A weak animal is easy prey so they avoid looking weak. So any tiny change needs to be noted.
I’m going to tag in a couple more experienced keepers to chime in and give some insight here.
@MissSkittles @Beman